Adiponectin Receptors and Pro-inflammatory Cytokines Are Modulated in Common Variable Immunodeficiency Patients: Correlation With Ig Replacement Therapy

Adiponectin Receptors and Pro-inflammatory Cytokines Are Modulated in Common Variable Immunodeficiency Patients: Correlation With Ig Replacement Therapy

Adiponectin exerts beneficial pleiotropic effects through three receptors, AdipoR1, AdipoR2, and T-cadherin; it also exerts immunomodulatory effects. We previously demonstrated that adiponectin levels are altered in common variable immunodeficiency disease (CVID). The purpose of the present study wa...

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Bibliographic Details
Main Authors: Rita Polito, Ersilia Nigro, Antonio Pecoraro, Maria Ludovica Monaco, Franco Perna, Alessandro Sanduzzi, Arturo Genovese, Giuseppe Spadaro, Aurora Daniele
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
adiponectin
common variable immunodeficiency
adiponectin receptors
leptin
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02812/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02812/full

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