Mitochondrion-NLRP3 inflammasome activation in macrophages: A novel mechanism of the anti-inflammatory effect of Notopterygium in rheumatoid arthritis treatment

Objective: The mechanism by which Notopterygium (NE) regulates the nucleotide‐binding, oligomerization domain (NOD)‐like receptor family and pyrin domain-containing 3 (NLRP3) inflammasome to treat rheumatoid arthritis (RA) was investigated to reveal the scientific implications of NE in RA treatment....

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Bibliographic Details
Main Authors: Xiangxiang Liu, Xiaomei Chen, Cheng Zhang, Meixia Huang, Hongmin Yu, Yingzheng Wang, Yinghao Wang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223013586