Host-mediated post-translational prenylation of novel Dot/Icm-translocated effectors of Legionella pneumophila

The Dot/Icm type IV translocated Ankyrin B (AnkB) effector of Legionella pneumophila is modified by the host prenylation machinery that anchors it into the outer leaflet of the Legionella-containing vacuole (LCV), which is essential for biological function of the effector in vitro and in vivo. Pre...

Full description

Bibliographic Details
Main Authors: Christopher T Price, Snake C Jones, Karen E Amundson, Yousef eAbu Kwaik
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2010.00131/full