When STING Meets Viruses: Sensing, Trafficking and Response

When STING Meets Viruses: Sensing, Trafficking and Response

To effectively defend against microbial pathogens, the host cells mount antiviral innate immune responses by producing interferons (IFNs), and hundreds of IFN-stimulated genes (ISGs). Upon recognition of cytoplasmic viral or bacterial DNAs and abnormal endogenous DNAs, the DNA sensor cGAS synthesize...

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Bibliographic Details
Main Authors: Zhaohe Li, Siqi Cai, Yutong Sun, Li Li, Siyuan Ding, Xin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
STING
DNA viruses
cellular trafficking
post translational modifications
immune responses
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02064/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02064/full

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