Decreased exosome-delivered miR-486-5p is responsible for the peritoneal metastasis of gastric cancer cells by promoting EMT progress

Abstract Background The present study aims to investigate the preliminary mechanism underlying the peritoneal metastasis of gastric cancer cells. Methods Exosomes from GC9811 cells (Con-Exo) and from GC9811-P cells (PM-Exo) were extracted by ultracentrifugation, which were identified with transmissi...

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Bibliographic Details
Main Authors: Xian-Ming Lin, Zhi-Jiang Wang, Yu-Xiao Lin, Hao Chen
Format: Article
Language:English
Published: BMC 2021-10-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:https://doi.org/10.1186/s12957-021-02381-5