Therapeutic resistance and optimal drug sequencing in HER2-positive metastatic breast cancer: unmet needs and future perspectives

In the last couple of decades substantial therapeutic improvements deeply influenced the treatment of HER2-positive metastatic breast cancer. The most impactful advancements were obtained especially in the first-line setting, with the trastuzumab/pertuzumab anti-HER2 double blockade, and in the seco...

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Bibliographic Details
Main Authors: Francesco Schettini, Fabiola Giudici, Daniele Generali
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023105755