Structure Elucidation and Functional Studies of a Novel β-hairpin Antimicrobial Peptide from the Marine Polychaeta <i>Capitella teleta</i>

Structure Elucidation and Functional Studies of a Novel β-hairpin Antimicrobial Peptide from the Marine Polychaeta <i>Capitella teleta</i>

Endogenous antimicrobial peptides (AMPs) are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. Among the most active and stable under physiological conditions AMPs are the peptides of animal origin that adopt a β-hairpin conformation stabilized by disulf...

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Bibliographic Details
Main Authors: Pavel V. Panteleev, Andrey V. Tsarev, Victoria N. Safronova, Olesia V. Reznikova, Ilia A. Bolosov, Sergei V. Sychev, Zakhar O. Shenkarev, Tatiana V. Ovchinnikova
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Marine Drugs
Subjects:
antimicrobial peptide
polychaeta
innate immunity
BRICHOS domain
recombinant peptide
β-hairpin structure
Online Access:https://www.mdpi.com/1660-3397/18/12/620

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https://www.mdpi.com/1660-3397/18/12/620

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