Single-cell RNA sequencing reveals the potential mechanism of heterogeneity of immunomodulatory properties of foreskin and umbilical cord mesenchymal stromal cells

Single-cell RNA sequencing reveals the potential mechanism of heterogeneity of immunomodulatory properties of foreskin and umbilical cord mesenchymal stromal cells

Abstract Background Mesenchymal stromal cells (MSCs) are heterogeneous populations. Heterogeneity exists within the same tissue and between different tissues. Some studies have found enormous heterogeneity in immunomodulatory function among MSCs derived from different tissues. Moreover, the underlyi...

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Bibliographic Details
Main Authors: Siyu Cai, Chuiqin Fan, Lichun Xie, Huifeng Zhong, Aijia Li, Siyu Lv, Maochuan Liao, Xixi Yang, Xing Su, Yue Wang, Hongwu Wang, Manna Wang, Peng Huang, Yulin Liu, Yu Wang, Yufeng Liu, Tianyou Wang, Yong Zhong, Lian Ma
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell & Bioscience
Subjects:
Mesenchymal stromal cells
Single-cell RNA sequencing
Heterogeneity of immunomodulatory function
Foreskin mesenchymal stromal cells
Human umbilical cord mesenchymal stromal cells
Online Access:https://doi.org/10.1186/s13578-022-00848-w

Internet

https://doi.org/10.1186/s13578-022-00848-w

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