The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

Cortical expansion and folding are often linked to the evolution of higher intelligence, but molecular and cellular mechanisms underlying cortical folding remain poorly understood. The hominoid-specific gene TBC1D3 undergoes segmental duplications during hominoid evolution, but its role in brain dev...

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Bibliographic Details
Main Authors: Xiang-Chun Ju, Qiong-Qiong Hou, Ai-Li Sheng, Kong-Yan Wu, Yang Zhou, Ying Jin, Tieqiao Wen, Zhengang Yang, Xiaoqun Wang, Zhen-Ge Luo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
neural progenitors
cortical folding
hominoid-specific gene
Online Access:https://elifesciences.org/articles/18197

Internet

https://elifesciences.org/articles/18197

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