Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice

Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice

The tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b/PEX5R) is an interaction partner and auxiliary subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, which are key for rhythm generation in the brain and in the heart. Since TRIP8b is expressed in cent...

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Bibliographic Details
Main Authors: Katharina Scherschel, Hanna Bräuninger, Andrea Mölders, Nadine Erlenhardt, Ehsan Amin, Christiane Jungen, Ulrike Pape, Diana Lindner, Dane M. Chetkovich, Nikolaj Klöcker, Christian Meyer
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
autonomic nervous system
TRIP8b
HCN channels
cardiac electrophysiology
Online Access:https://www.mdpi.com/1422-0067/22/9/4772

Internet

https://www.mdpi.com/1422-0067/22/9/4772

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