Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy

Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy

Background: Glioblastoma is the most lethal primary brain malignancy in adults. Standard of care treatment, consisting of temozolomide (TMZ) and adjuvant radiotherapy (RT), mostly does not prevent local recurrence. The inability of drugs to enter the brain, in particular antibody-based drugs and rad...

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Bibliographic Details
Main Authors: Omer Gal, Oshra Betzer, Liat Rousso-Noori, Tamar Sadan, Menachem Motiei, Maxim Nikitin, Dinorah Friedmann-Morvinski, Rachela Popovtzer, Aron Popovtzer
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Nanotheranostics
Subjects:
glioblastoma
gold nanoparticles
cetuximab
blood–brain barrier
radiotherapy
Online Access:https://www.mdpi.com/2624-845X/3/4/12

Internet

https://www.mdpi.com/2624-845X/3/4/12

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