Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy
Nemaline myopathy (NM) is one of the most common forms of congenital myopathy, and affects either fast myofibers, slow myofibers, or both. However, an animal model for congenital myopathy with fast-myofiber-specific atrophy is not available. Furthermore, mutations in the leiomodin-3 (LMOD3) gene hav...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-06-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/8/6/635 |