Structural characterization of the mitochondrial Ca2+ uniporter provides insights into Ca2+ uptake and regulation
Summary: The mitochondrial uniporter is a Ca2+-selective ion-conducting channel in the inner mitochondrial membrane that is involved in various cellular processes. The components of this uniporter, including the pore-forming membrane subunit MCU and the modulatory subunits MCUb, EMRE, MICU1, and MIC...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221008634 |