Structural characterization of the mitochondrial Ca2+ uniporter provides insights into Ca2+ uptake and regulation

Structural characterization of the mitochondrial Ca2+ uniporter provides insights into Ca2+ uptake and regulation

Summary: The mitochondrial uniporter is a Ca2+-selective ion-conducting channel in the inner mitochondrial membrane that is involved in various cellular processes. The components of this uniporter, including the pore-forming membrane subunit MCU and the modulatory subunits MCUb, EMRE, MICU1, and MIC...

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Bibliographic Details
Main Authors: Wenping Wu, Jimin Zheng, Zongchao Jia
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Ion
Molecular biology
Membranes
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008634

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