Suppressor of Cytokine Signaling-1/STAT1 Regulates Renal Inflammation in Mesangial Proliferative Glomerulonephritis Models

Suppressor of Cytokine Signaling-1/STAT1 Regulates Renal Inflammation in Mesangial Proliferative Glomerulonephritis Models

Mesangial proliferative glomerulonephritis (MsGN) is a significant global threat to public health. Inflammation plays a crucial role in MsGN; however, the underlying mechanism remains unknown. Herein, we demonstrate that suppression of the cytokine signaling-1 (SOCS1)/signal transducer and activator...

Full description

Bibliographic Details
Main Authors: Jiuxu Bai, Lingling Wu, Xiaoniao Chen, Liqiang Wang, Qinggang Li, Yingjie Zhang, Jie Wu, Guangyan Cai, Xiangmei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
inflammation
mesangial proliferative glomerulonephritis
SOCS1
STAT1
MHC class II
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01982/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01982/full

Similar Items