RFRP-3 Influences Apoptosis and Steroidogenesis of Yak Cumulus Cells and Compromises Oocyte Meiotic Maturation and Subsequent Developmental Competence

RFRP-3 Influences Apoptosis and Steroidogenesis of Yak Cumulus Cells and Compromises Oocyte Meiotic Maturation and Subsequent Developmental Competence

RF amide-related peptide 3 (RFRP-3), a mammalian ortholog of gonadotropin-inhibitory hormone (GnIH), is identified to be a novel inhibitory endogenous neurohormonal peptide that regulates mammalian reproduction by binding with specific G protein-coupled receptors (GPRs) in various species. Herein, o...

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Bibliographic Details
Main Authors: Xianrong Xiong, Yulei Hu, Bangting Pan, Yanjin Zhu, Xixi Fei, Qinhui Yang, Yumian Xie, Yan Xiong, Daoliang Lan, Wei Fu, Jian Li
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
RFRP-3
apoptosis
steroidogenesis
cumulus cell
development
Online Access:https://www.mdpi.com/1422-0067/24/8/7000

Internet

https://www.mdpi.com/1422-0067/24/8/7000

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