Statistical genetics and polygenic risk score for precision medicine

Abstract The prediction of disease risks is an essential part of personalized medicine, which includes early disease detection, prevention, and intervention. The polygenic risk score (PRS) has become the standard for quantifying genetic liability in predicting disease risks. PRS utilizes single-nucl...

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Bibliographic Details
Main Authors: Takahiro Konuma, Yukinori Okada
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Inflammation and Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s41232-021-00172-9