Statistical genetics and polygenic risk score for precision medicine

Statistical genetics and polygenic risk score for precision medicine

Abstract The prediction of disease risks is an essential part of personalized medicine, which includes early disease detection, prevention, and intervention. The polygenic risk score (PRS) has become the standard for quantifying genetic liability in predicting disease risks. PRS utilizes single-nucl...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Takahiro Konuma, Yukinori Okada
Format:	Artikel
Sprache:	English
Veröffentlicht:	BMC 2021-06-01
Schriftenreihe:	Inflammation and Regeneration
Schlagworte:	Statistical genomics Genome-wide association study Polygenic risk score Precision medicine
Online Zugang:	https://doi.org/10.1186/s41232-021-00172-9

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