Impact of leptin deficiency on male tibia and vertebral body 3D bone architecture independent of changes in body weight

Abstract Leptin an adipokine with potent effects on energy balance and body weight plays an important role in defining bone architecture in growing mammals. However, major changes in body weight can also influence morphology of trabecular and cortical bone. Therefore, we examined the impact of lepti...

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Bibliographic Details
Main Authors: Alexander Williamson, Alexandre daSilva, Jussara M. doCarmo, Christine L. Le Maitre, John E. Hall, Nicola Aberdein
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15832