Characterization of the EM66 Biomarker in the Pituitary and Plasma of Healthy Subjects With Different Gonadotroph Status and Patients With Gonadotroph Tumor

Characterization of the EM66 Biomarker in the Pituitary and Plasma of Healthy Subjects With Different Gonadotroph Status and Patients With Gonadotroph Tumor

Granins and their derived-peptides are useful markers of secretion from normal and tumoral neuroendocrine cells. The need to identify new diagnostic markers for neuroendocrine tumors, including pituitary tumors prompted us to determine plasma levels of the secretogranin II-derived peptide EM66 in he...

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Bibliographic Details
Main Authors: Johann Guillemot, Marlène Guérin, Anne-Françoise Cailleux, Antoine-Guy Lopez, Jean-Marc Kuhn, Youssef Anouar, Laurent Yon
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Endocrinology
Subjects:
EM66
pituitary
gonadotroph tumor
plasma marker
secretogranin II
neuroendocrine tumors
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00102/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00102/full

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