SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation

SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation

Summary: cGMP is critical to a variety of cellular processes, but the available tools to interfere with endogenous cGMP lack cellular and subcellular specificity. We introduce SponGee, a genetically encoded chelator of this cyclic nucleotide that enables in vitro and in vivo manipulations in single...

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Bibliographic Details
Main Authors: Oriol Ros, Yvrick Zagar, Solène Ribes, Sarah Baudet, Karine Loulier, Sandrine Couvet, Delphine Ladarre, Alain Aghaie, Alice Louail, Christine Petit, Yves Mechulam, Zsolt Lenkei, Xavier Nicol
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719307417

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http://www.sciencedirect.com/science/article/pii/S2211124719307417

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