Therapeutic efficacy of valproic acid in a combined monocrotaline and chronic hypoxia rat model of severe pulmonary hypertension.

<h4>Background</h4>Pulmonary hypertension (PH) is a serious disease with poor prognosis. Reports show that cells in remodeled pulmonary arteries of PH patients have similar characteristics to cancer cells, such as exuberant inflammation, increased proliferation, and decreased apoptosis....

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Main Authors: Beidi Lan, Emiko Hayama, Nanako Kawaguchi, Yoshiyuki Furutani, Toshio Nakanishi
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117211&type=printable