Influence of High Hemoglobin-Oxygen Affinity on Humans During Hypoxia

Humans elicit a robust series of physiological responses to maintain adequate oxygen delivery during hypoxia, including a transient reduction in hemoglobin-oxygen (Hb-O2) affinity. However, high Hb-O2 affinity has been identified as a beneficial adaptation in several species that have been exposed t...

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Bibliographic Details
Main Authors: Kevin L. Webb, Paolo B. Dominelli, Sarah E. Baker, Stephen A. Klassen, Michael J. Joyner, Jonathon W. Senefeld, Chad C. Wiggins
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.763933/full