Nationwide pharmacovigilance data for cetuximab-induced anaphylaxis and predictive model validation using prospective specific IgE detection

Background: Cetuximab (chimeric monoclonal antibody to human epidermal growth factor receptor) is used to treat colorectal and head and neck cancers. Due to cross-reactivity with galactose-α-1,3-galactose (alpha-gal), it can induce hypersensitivity even at first administration. We aimed to determine...

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Bibliographic Details
Main Authors: Kyung Hee Park, Jongsun Lee, Seung Hoon Beom, Sang Joon Shin, Joong Bae Ahn, Sung-Ryeol Kim, Jae-Hyun Lee, Jung-Won Park
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:World Allergy Organization Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455121000478