Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide Interactions

Technologies for discovering peptides as potential therapeutics have rapidly advanced in recent years with significant interest from both academic and pharmaceutical labs. These advancements in turn drive the need for new computational tools to design peptides for purposes of advancing lead molecule...

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Autori principali: Jeffrey K. Holden, Ryan Pavlovicz, Alberto Gobbi, Yifan Song, Christian N. Cunningham
Natura: Articolo
Lingua:English
Pubblicazione: Frontiers Media S.A. 2022-04-01
Serie:Frontiers in Molecular Biosciences
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Accesso online:https://www.frontiersin.org/articles/10.3389/fmolb.2022.848689/full