LINC00887 promotes GCN5-dependent H3K27cr level and CRC metastasis via recruitment of YEATS2 and enhancing ETS1 expression

LINC00887 promotes GCN5-dependent H3K27cr level and CRC metastasis via recruitment of YEATS2 and enhancing ETS1 expression

Abstract Recent observations have revealed upregulation of H3K27cr in colorectal cancer (CRC) tissues; however, the underlying cause remains elusive. This study aimed to investigate the mechanism of H3K27cr upregulation and its roles in CRC metastasis. Clinically, our findings showed that H3K27cr se...

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Bibliographic Details
Main Authors: Meijian Liao, Wendan Zheng, Yifan Wang, Mengting Li, Xiaolin Sun, Nan Liu, Jia Yao, Fuxing Dong, Qingling Wang, Yu Ma, Jie Mou
Format: Article
Language:English
Published: Nature Publishing Group 2024-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07091-w

Internet

https://doi.org/10.1038/s41419-024-07091-w

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