Identification of Crucial Residues in α-Conotoxin EI Inhibiting Muscle Nicotinic Acetylcholine Receptor

Identification of Crucial Residues in α-Conotoxin EI Inhibiting Muscle Nicotinic Acetylcholine Receptor

&#945;-Conotoxins (&#945;-CTxs) are small disulfide-rich peptides from venom of <i>Conus</i> species that target nicotinic acetylcholine receptors (nAChRs). The muscle-type nAChRs have been recognized as a potential target for several diseases, such as myogenic disorders, muscle...

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Bibliographic Details
Main Authors: Jiong Ning, Jie Ren, Yang Xiong, Yong Wu, Manqi Zhangsun, Dongting Zhangsun, Xiaopeng Zhu, Sulan Luo
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Toxins
Subjects:
muscle-type nachr
α-ctx ei
ala-scan mutagenesis
tevc
cd spectroscopy
Online Access:https://www.mdpi.com/2072-6651/11/10/603

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https://www.mdpi.com/2072-6651/11/10/603

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