Spatial immunophenotypes orchestrate prognosis in triple-negative breast cancer with Miller-Payne grade 4 following neoadjuvant chemotherapy

Abstract Some triple-negative breast cancer (TNBC) patients evaluated as Miller-Payne 4 with ypN0 after neoadjuvant chemotherapy (NACT) who have better prognoses should avoid escalation of therapy. We aim to identify these patients by evaluating pretherapeutic spatial distributions of immunophenotyp...

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Bibliographic Details
Main Authors: Jianli Ma, Yuwei Deng, Dawei Chen, Xiaomei Li, Zhiyong Yu, Haibo Wang, Lei Zhong, Yingjie Li, Chengqin Wang, Xiang Li, Jinming Yu, Qingyuan Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00565-8