Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay.

Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay.

The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...

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Bibliographic Details
Main Authors: Vasundhara Sharma, Jennifer J Jordan, Yari Ciribilli, Michael A Resnick, Alessandra Bisio, Alberto Inga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4493129?pdf=render

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http://europepmc.org/articles/PMC4493129?pdf=render

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