Whole-exome sequencing reveals novel variants of monogenic diabetes in Tunisia: impact on diagnosis and healthcare management

Whole-exome sequencing reveals novel variants of monogenic diabetes in Tunisia: impact on diagnosis and healthcare management

Introduction: Monogenic diabetes (MD) accounts for 3%–6% of all cases of diabetes. This prevalence is underestimated due to its overlapping clinical features with type 1 and type 2 diabetes. Hence, genetic testing is the most appropriate tool for obtaining an accurate diagnosis. In Tunisia, few coho...

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Bibliographic Details
Main Authors: Nadia Kheriji, Hamza Dallali, Ismail Gouiza, Meriem Hechmi, Faten Mahjoub, Mehdi Mrad, Asma Krir, Manel Soltani, Hajer Trabelsi, Walid Hamdi, Afef Bahlous, Melika Ben Ahmed, Henda Jamoussi, Rym Kefi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Genetics
Subjects:
whole-exome sequencing
bioinformatics analysis
3D structural modeling
syndromic diabetes
genetic diagnosis
North African population
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1224284/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1224284/full

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