Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice

Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice

Specific therapeutics are not available for acute lung injury (ALI) induced by ricin toxin (RT). Inhibiting the host immune response in the course of pulmonary ricinosis is hypothesized to be of benefit and can be achieved by impairing granulocyte-macrophage colony-stimulating factor (GM-CSF) signal...

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Bibliographic Details
Main Authors: Fuliang Zong, Sha Li, Yifeng Wang, Nan Xiao, Mengyun Deng, Zhipeng Zhang, Duo Su, Bo Gao, Dongsheng Zhou, Lingfei Hu, Huiying Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
RT
Csf2ra
ALI
RNA-Seq
GM-CSF receptor
inflammation response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.900755/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.900755/full

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