3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis

3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis

APAP is one of the most commonly used antipyretic and pain medications, but excessive use can cause liver toxicity and damage. 3,4-dihydroxyphenylethyl alcohol glycoside (DAG) is a component isolated from Sargentodoxa cuneata known to have anti-apoptotic, anti-oxidation and anti-inflammatory effects...

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Bibliographic Details
Main Authors: Tianyu Liu, Lei Yang, Hejun Gao, Yuzhen Zhuo, Zhengwei Tu, Yongqin Wang, Jing Xun, Qi Zhang, Lanqiu Zhang, Ximo Wang
Format: Article
Language:English
Published: PeerJ Inc. 2022-03-01
Series:PeerJ
Subjects:
Acetaminophen
Acute liver failure
Ferroptosis
Pyroptosis
3,4-dihydroxyphenylethyl alcohol glycoside
Online Access:https://peerj.com/articles/13082.pdf

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https://peerj.com/articles/13082.pdf

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