3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis
APAP is one of the most commonly used antipyretic and pain medications, but excessive use can cause liver toxicity and damage. 3,4-dihydroxyphenylethyl alcohol glycoside (DAG) is a component isolated from Sargentodoxa cuneata known to have anti-apoptotic, anti-oxidation and anti-inflammatory effects...
Main Authors: | Tianyu Liu, Lei Yang, Hejun Gao, Yuzhen Zhuo, Zhengwei Tu, Yongqin Wang, Jing Xun, Qi Zhang, Lanqiu Zhang, Ximo Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2022-03-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/13082.pdf |
Similar Items
-
Role of Pyroptosis in Acetaminophen-Induced Hepatotoxicity
by: Hartmut Jaeschke, et al.
Published: (2022-12-01) -
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes
by: Yifei Yang, et al.
Published: (2023-07-01) -
Naturally occuring glycosides /
by: Ikan, Raphael
Published: (1999) -
Acetaminophen overdose associated with double serum concentration peaks
by: Cristian Papazoglu, et al.
Published: (2015-12-01) -
Synthesis and characterization of glycosides /
by: 178995 Brito Arias, Marco Augusto
Published: (2007)