A protocol to extract cell-type-specific signatures from differentially expressed genes in bulk-tissue RNA-seq
Summary: Bulk-tissue RNA-seq is widely used to dissect variation in gene expression levels across tissues and under different experimental conditions. Here, we introduce a protocol that leverages existing single-cell expression data to deconvolve patterns of cell-type-specific gene expression in dif...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-03-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166722000016 |