A protocol to extract cell-type-specific signatures from differentially expressed genes in bulk-tissue RNA-seq

Summary: Bulk-tissue RNA-seq is widely used to dissect variation in gene expression levels across tissues and under different experimental conditions. Here, we introduce a protocol that leverages existing single-cell expression data to deconvolve patterns of cell-type-specific gene expression in dif...

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Bibliographic Details
Main Authors: Angel Marquez-Galera, Liset M. de la Prida, Jose P. Lopez-Atalaya
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722000016