Structural and topographic dynamics of pulmonary histopathology and local cytokine profiles in Paracoccidioides brasiliensis conidia-infected mice.

BACKGROUND: Paracoccidioidomycosis (PCM), an endemic systemic mycosis caused by the fungus Paracoccidioides brasiliensis (Pb), usually results in severe lung damage in patients. METHODS AND FINDINGS: Considering the difficulties to sequentially study the infection in humans, this work was done in mi...

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Bibliographic Details
Main Authors: Damaris Lopera, Tonny W Naranjo, Oswaldo G Cruz, Angela Restrepo, Luz Elena Cano, Henrique Leonel Lenzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3134433?pdf=render