In Vivo Brain Oxidative Stress Model Induced by Microinjection of Sodium Nitroprusside in Mice
Sodium nitroprusside (SNP) is widely used as a potent vasodilator and a nitric oxide (NO) donor, whereas the cytotoxicity of SNP has been well documented. SNP releases several potentially toxic products such as cyanide anion, NO, and iron. We investigated the mechanisms of cell death and motor dysfu...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319304487 |