A molecular mechanism of mitotic centrosome assembly in Drosophila

A molecular mechanism of mitotic centrosome assembly in Drosophila

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both...

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Bibliographic Details
Main Authors: Paul T Conduit, Jennifer H Richens, Alan Wainman, James Holder, Catarina C Vicente, Metta B Pratt, Carly I Dix, Zsofia A Novak, Ian M Dobbie, Lothar Schermelleh, Jordan W Raff
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
centrosome
PCM
centrosome maturation
live super-resolution
FRAP
Online Access:https://elifesciences.org/articles/03399

Internet

https://elifesciences.org/articles/03399

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