Pharmacological and In Silico Analysis of Oat Avenanthramides as EGFR Inhibitors: Effects on EGF-Induced Lung Cancer Cell Growth and Migration

Pharmacological and In Silico Analysis of Oat Avenanthramides as EGFR Inhibitors: Effects on EGF-Induced Lung Cancer Cell Growth and Migration

<i>Avena sativa</i> L. is a wholegrain cereal and an important edible crop. Oats possesses high nutritional and health promoting values and contains high levels of bioactive compounds, including a group of phenolic amides, named avenanthramides (Avns), exerting antioxidant, anti-inflamma...

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Bibliographic Details
Main Authors: Lorenza Trabalzini, Jasmine Ercoli, Alfonso Trezza, Irene Schiavo, Giulia Macrì, Andrea Moglia, Ottavia Spiga, Federica Finetti
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
avenanthramides
EGFR
lung cancer
avenanthramide C
docking simulation
classical molecular dynamics simulation
Online Access:https://www.mdpi.com/1422-0067/23/15/8534

Internet

https://www.mdpi.com/1422-0067/23/15/8534

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