Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice

Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice

Abstract Schistosomiasis is a parasitic disease affecting more than 250 million people worldwide. The transcription factor c-Jun, which is induced in S. mansoni infection-associated liver disease, can promote hepatocyte survival but can also trigger hepatocellular carcinogenesis. We aimed to analyze...

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Bibliographic Details
Main Authors: Lukas Härle, Verena von Bülow, Lukas Knedla, Frederik Stettler, Heike Müller, Daniel Zahner, Simone Haeberlein, Anita Windhorst, Annette Tschuschner, Monika Burg-Roderfeld, Kernt Köhler, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47646-z

Internet

https://doi.org/10.1038/s41598-023-47646-z

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