Optimized reduced representation bisulfite sequencing reveals tissue-specific mCHH islands in maize

Abstract Background DNA methylation plays important roles in many regulatory processes in plants. It is economically infeasible to profile genome-wide DNA methylation at a single-base resolution in maize, given its genome size of ~2.5 Gb. As an alternative, we adapted region of interest (ROI)-direct...

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Bibliographic Details
Main Authors: Fei-Man Hsu, Ming-Ren Yen, Chi-Ting Wang, Chien-Yu Lin, Chung-Ju Rachel Wang, Pao-Yang Chen
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-017-0148-y