Optimized reduced representation bisulfite sequencing reveals tissue-specific mCHH islands in maize
Abstract Background DNA methylation plays important roles in many regulatory processes in plants. It is economically infeasible to profile genome-wide DNA methylation at a single-base resolution in maize, given its genome size of ~2.5 Gb. As an alternative, we adapted region of interest (ROI)-direct...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
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Series: | Epigenetics & Chromatin |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13072-017-0148-y |