Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome

Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome

Large/abnormal offspring syndrome (LOS/AOS) is a congenital overgrowth syndrome reported in ruminants produced by assisted reproduction (ART-LOS) which exhibit global disruption of the epigenome and transcriptome. LOS/AOS shares phenotypes and epigenotypes with the human congenital overgrowth condit...

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Bibliographic Details
Main Authors: Yahan Li, Jordana Sena Lopes, Pilar Coy-Fuster, Rocío Melissa Rivera
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Epigenetics
Subjects:
spontaneous large offspring syndrome
abnormal offspring syndrome
dna methylation
genomic imprinting
igf2r
bovine
reproductive fluids
assisted reproductive technologies
Online Access:http://dx.doi.org/10.1080/15592294.2022.2067938

Internet

http://dx.doi.org/10.1080/15592294.2022.2067938

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