Characterization of Hair Cell-Like Cells Converted From Supporting Cells After Notch Inhibition in Cultures of the Organ of Corti From Neonatal Gerbils

Characterization of Hair Cell-Like Cells Converted From Supporting Cells After Notch Inhibition in Cultures of the Organ of Corti From Neonatal Gerbils

The senses of hearing and balance depend upon hair cells, the sensory receptors of the inner ear. Hair cells transduce mechanical stimuli into electrical activity. Loss of hair cells as a result of aging or exposure to noise and ototoxic drugs is the major cause of noncongenital hearing and balance...

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Bibliographic Details
Main Authors: Yi Li, Shuping Jia, Huizhan Liu, Tomoko Tateya, Weiwei Guo, Shiming Yang, Kirk W. Beisel, David Z. Z. He
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
notch signaling
hair cells
stereocilia formation
mechanotransduction
development
hearing loss
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00073/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2018.00073/full

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