Single molecule mass photometry reveals the dynamic oligomerization of human and plant peroxiredoxins

Summary: Protein oligomerization is central to biological function and regulation, yet its experimental quantification and measurement of dynamic transitions in solution remain challenging. Here, we show that single molecule mass photometry quantifies affinity and polydispersity of heterogeneous pro...

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Bibliographic Details
Main Authors: Michael Liebthal, Manish Singh Kushwah, Philipp Kukura, Karl-Josef Dietz
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422101227X