4078 Identification of distinct fibroblast populations with unique roles in pancreatic cancer progression and tumor immunity

4078 Identification of distinct fibroblast populations with unique roles in pancreatic cancer progression and tumor immunity

OBJECTIVES/GOALS: The desmoplastic reaction in PDAC involves a significant accumulation of immune cells and fibroblasts.The functional diversity of carcinoma associated fibroblasts (CAFs) remains largely unknown, and identification of immune regulating subsets would have a substantial impact in augm...

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Bibliographic Details
Main Authors:	Josephine Kebbeh Darpolor, Xiaofeng Zheng, Sujuan Yang, Hikaru Sugimoto, Julienne Carstens, Pedro Correa de Sampiao, Valerie LeBleu, Raghu Kalluri
Format:	Article
Language:	English
Published:	Cambridge University Press 2020-06-01
Series:	Journal of Clinical and Translational Science
Online Access:	https://www.cambridge.org/core/product/identifier/S2059866120003015/type/journal_article

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