Using ribosomal protein genes as reference: a tale of caution.

BACKGROUND: Housekeeping genes are needed in every tissue as their expression is required for survival, integrity or duplication of every cell. Housekeeping genes commonly have been used as reference genes to normalize gene expression data, the underlying assumption being that they are expressed in...

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Bibliographic Details
Main Authors: Lieven Thorrez, Katrijn Van Deun, Léon-Charles Tranchevent, Leentje Van Lommel, Kristof Engelen, Kathleen Marchal, Yves Moreau, Iven Van Mechelen, Frans Schuit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2267211?pdf=render