Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

Staphylococcus aureus is implicated in disease progression in cutaneous T-cell lymphoma (CTCL). Here, we demonstrate that malignant T cell lines derived from CTCL patients as well as primary malignant CD4+ T cells from Sézary syndrome patients are considerably more resistant to alpha-toxin-induced c...

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Bibliographic Details
Main Authors: Edda Blümel, Andreas Willerslev-Olsen, Maria Gluud, Lise M. Lindahl, Simon Fredholm, Claudia Nastasi, Thorbjørn Krejsgaard, Bas G. J. Surewaard, Sergei B. Koralov, Tengpeng Hu, Jenny L. Persson, Charlotte Menné Bonefeld, Carsten Geisler, Lars Iversen, Jürgen C. Becker, Mads Hald Andersen, Anders Woetmann, Terkild Brink Buus, Niels Ødum
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:OncoImmunology
Subjects:
cutaneous t-cell lymphoma
staphylococcus aureus
alpha-toxin
disintegrin and metalloproteinase domain-containing protein 10
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1641387

Internet

http://dx.doi.org/10.1080/2162402X.2019.1641387

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