Exosome-guided direct reprogramming of tumor-associated macrophages from protumorigenic to antitumorigenic to fight cancer

Exosome-guided direct reprogramming of tumor-associated macrophages from protumorigenic to antitumorigenic to fight cancer

Highly immunosuppressive tumor microenvironment containing various protumoral immune cells accelerates malignant transformation and treatment resistance. In particular, tumor-associated macrophages (TAMs), as the predominant infiltrated immune cells in a tumor, play a pivotal role in regulating the...

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Bibliographic Details
Main Authors: Hyosuk Kim, Hyun-Ju Park, Hyo Won Chang, Ji Hyun Back, Su Jin Lee, Yae Eun Park, Eun Hye Kim, Yeonsun Hong, Gijung Kwak, Ick Chan Kwon, Ji Eun Lee, Yoon Se Lee, Sang Yoon Kim, Yoosoo Yang, Sun Hwa Kim
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-07-01
Series:Bioactive Materials
Subjects:
Exosome
Cancer therapy
Tumor microenvironment
Tumor-associated macrophage
Direct conversion
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2200319X

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X2200319X

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