SCOUR: a stepwise machine learning framework for predicting metabolite-dependent regulatory interactions

Abstract Background The topology of metabolic networks is both well-studied and remarkably well-conserved across many species. The regulation of these networks, however, is much more poorly characterized, though it is known to be divergent across organisms—two characteristics that make it difficult...

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Bibliographic Details
Main Authors: Justin Y. Lee, Britney Nguyen, Carlos Orosco, Mark P. Styczynski
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04281-7