Formation of macrophage phenotupe in inflammatory and fibrogenic response: The role of mevalonate pathway and nuclear receptors LXR

Free cholesterol (Ch) and its oxidative derivatives, oxysterols (OS), are often accumulated in macrophages during chronic inflammation and atherogenesis. The effects of Ch and OS on the balance of pro- and anti-inflammatory cytokines in inflammatory response and the role of mevalonate pathway in the...

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Bibliographic Details
Main Authors: Ya. Sh. Shvarts, M. I. Chasovskikh, O. M. Dolganova
Format: Article
Language:Russian
Published: Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2014-09-01
Series:Атеросклероз
Subjects:
Online Access:https://ateroskleroz.elpub.ru/jour/article/view/713/655