Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs

Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs

Abstract Medulloblastoma (MB) is the most common malignant brain tumor in children. There remains an unmet need for diagnostics to sensitively detect the disease, particularly recurrences. Cerebrospinal fluid (CSF) provides a window into the central nervous system, and liquid biopsy of CSF could pro...

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Bibliographic Details
Main Authors: Bongyong Lee, Iqbal Mohamad, Rudramani Pokhrel, Rabi Murad, Menglang Yuan, Stacie Stapleton, Chetan Bettegowda, George Jallo, Charles G. Eberhart, Timothy Garrett, Ranjan J. Perera
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Acta Neuropathologica Communications
Subjects:
Circular RNA
Lipidomics
Medulloblastoma
Metabolomics
TCA
Transcriptomics
Online Access:https://doi.org/10.1186/s40478-022-01326-7

Internet

https://doi.org/10.1186/s40478-022-01326-7

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